An application of decellularized membrane as guided tissue regeneration

Decellularized Extracellular Matrix (DECM) has been established as a biomaterial that retains the natural properties of a tissue, promotes cell proliferation and cell differentiation. Periodontal regeneration requires the neovascularization niches and the proliferation and differentiation of the involved cells. DECM have various advantages and qualities in terms of stimulating periodontal tissue regeneration. Several methods for improving mechanical strength of the scaffolds have been identified like, crosslinking which is to enhance regenerative potential. This review focuses on the ability of DECM to repair damaged tissue in periodontal tissue engineering and addresses the future direction of periodontal regeneration in particular area.