医学
甲状旁腺切除术
西那卡塞特
维生素D与神经学
疾病
继发性甲状旁腺功能亢进
肾脏疾病
甲状旁腺功能亢进
生活质量(医疗保健)
重症监护医学
内分泌学
泌尿科
内科学
甲状旁腺激素
钙
护理部
作者
Lorenza Magagnoli,Paola Ciceri,Mario Cozzolino
标识
DOI:10.1080/13543784.2024.2369307
摘要
Introduction Secondary hyperparathyroidism (SHPT) is a common complication of chronic kidney disease (CKD). It begins as an adaptive increase in parathyroid hormone levels to prevent calcium and phosphate derangements. Over time, this condition becomes maladaptive and is associated with increased morbidity and mortality. Current therapies encompass phosphate-lowering strategies, vitamin D analogues, calcimimetics and parathyroidectomy. These approaches harbor inherent limitations, stimulating interest in the development of new drugs for SHPT to overcome these limitations and improve survival and quality of life among CKD patients.
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