特发性肺纤维化
发病机制
肺纤维化
信号转导
医学
纤维化
免疫学
生物信息学
生物
肺
病理
内科学
遗传学
作者
Yang Zhou,Tingting Ling,Weihong Shi
标识
DOI:10.1186/s12931-024-02878-z
摘要
Abstract Idiopathic Pulmonary Fibrosis (IPF) represents a chronic and progressive pulmonary disorder distinguished by a notable mortality rate. Despite the elusive nature of the pathogenic mechanisms, several signaling pathways have been elucidated for their pivotal roles in the progression of this ailment. This manuscript aims to comprehensively review the existing literature on the signaling pathways linked to the pathogenesis of IPF, both within national and international contexts. The objective is to enhance the comprehension of the pathogenic mechanisms underlying IPF and offer a scholarly foundation for the advancement of more efficacious therapeutic strategies, thereby fostering research and clinical practices within this domain.
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