Comparing Real‐World Outcomes of Catheter‐Directed Thrombolysis and Catheter‐Based Thrombectomy in Acute Pulmonary Embolism: A Post PEERLESS Analysis

The recently published PEERLESS trial compared catheter-directed thrombolysis (CDT) and catheter-based thrombectomy (CBT) in acute pulmonary embolism (PE). However, it included a low proportion of patients with contraindications to thrombolytic therapy (4.4%), leaving uncertainty about how CDT would perform relative to CBT in a real-world cohort with higher bleeding risk.