腺癌
脂肪酸代谢
机制(生物学)
肺
生物信息学
生物
癌症研究
计算生物学
基因
内科学
医学
癌症
遗传学
哲学
认识论
作者
Yang Liu,Xingshu Zhang,Xuechao Cheng,Qian Luo,Mingyang Yu,Kaijun Long,Wendong Qu,Yang Tang,Ming Gong,Lubiao Liang,Xixian Ke,Yimin Song
标识
DOI:10.3389/fgene.2022.990153
摘要
Lung adenocarcinoma (LUAD), a malignant respiratory tumor with an extremely poor prognosis, has troubled the medical community all over the world. According to recent studies, fatty acid metabolism (FAM) and long non-coding RNAs (lncRNAs) regulation have shown exciting results in tumor therapy. In this study, the original LUAD patient data was obtained from the TCGA database, and 12 FAM-related lncRNAs (AL390755.1, AC105020.6, TMPO-AS1, AC016737.2, AC127070.2, LINC01281, AL589986.2, GAS6-DT, AC078993.1, LINC02198, AC007032.1, and AL021026.1) that were highly related to the progression of LUAD were finally identified through bioinformatics analysis, and a risk score model for clinical reference was constructed. The window explores the immunology and molecular mechanism of LUAD, aiming to shed the hoping light on LUAD treatment.
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