[Prognostic significance of cell proliferation, microvascular density and androgen receptor level in prostatic adenocarcinoma].

Our study was concerned with prognostic significance of immunophenotypical features of prostate adenocarcinoma such as Ki-67 proliferation, androgen receptors (AR), microvascular density (MVD) in the stroma and tumor glands. Ki-67, AR and MVD expression correlated inversely with PSA level during hormonotherapy (r=0.24-0.39) as well as tumor cell differentiation grade (r=0.23-0.25). High expression of the said markers involved reduced efficiency of hormonotherapy.