Isolation and identification of chemical constituents in the lipid-lowering fraction of Flos Helichrysum arenarium(II)

Objective To study the chemical constituents in the lipid-lowering fraction of Flos Helichrysum arenarium.Methods The chemical constituents were isolated by various methods of isolation(silica gel,ODS and HPLC column chromatography)and their structures were elucidated by the analysis of spectral data and chemical properties.Results Eleven compounds were identified as syringin(1),dihydrosyringin(2),(E)-4-hydroxybenzalacetone-3-O-β-D-glucopyranoside(3),4-allyl-2-methoxyphenyl-1-O-β-D-apiofuranosyl-(1-6)-O-β-D-glucopyranoside(4),orcinol-β-D-glucopyranoside(5),7-hydroxy-5-methoxyphthalide-7-O-β-D-glucopyranoside(6),5,7-dihydroxyphthalide-7-O-β-D-glucopyranoside(7),undulatoside A(8),adenosine(9),maltol-3-O-β-D-apiofuranosyl-(1-6)-β-D-glucopyranoside(10),and 2,4,6-trihydroxylacetophenone-2,4-di-O-β-D-glucopyranoside(11).Conclusions Compounds 1-11 are obtained from Helichrysum for the first time.