立体光刻
3D生物打印
球体
3D打印
计算机科学
组织工程
生物加工
领域(数学)
纳米技术
工程类
生物医学工程
系统工程
机械工程
材料科学
生物
细胞培养
数学
纯数学
遗传学
作者
T. J. Sego,Nicanor I. Moldovan,Andrés Tovar
出处
期刊:Elsevier eBooks
[Elsevier]
日期:2017-10-12
卷期号:: 269-281
标识
DOI:10.1016/b978-0-12-811718-7.00015-0
摘要
Additive manufacturing has contributed significantly to the development of new surgical and diagnostic aids, personalized medical devices, implants, and prostheses. Now, it aspires to the direct digital manufacturing of living tissue, organs, and body parts. This can be achieved using three-dimensional (3D) bioprinting techniques in which the printing medium consists of biomaterials and living cells. Several 3D bioprinting methods are currently available, including inkjet, extrusion, and stereolithography. An emerging approach is the creation three-dimensional cellular patterns by the use of cell spheroids. The optimal application and further development of 3D bioprinting techniques could largely benefit from computational models capable of predicting the complex behavior of the printed cellular structures on multiple scales. This book chapter summarizes the state of the art of computational models in this field, with an emphasis on agent-based approaches and cell spheroid-based 3D bioprinting.
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