生物
外显子
内含子
环状RNA
多嘧啶束
计算生物学
核糖核酸
遗传学
基因亚型
剪接体
作者
Anke J. Tijsen,Lucía Cócera Ortega,Yolan J. Reckman,Xiaolei Zhang,Ingeborg van der Made,Simona Aufiero,Jiuru Li,Selina C. Kamps,Anouk van den Bout,Harsha D. Devalla,Karin Y. van Spaendonck-Zwarts,Stefan Engelhardt,Lior Gepstein,James S. Ware,Yigal M. Pinto
出处
期刊：Circulation
[Ovid Technologies (Wolters Kluwer)]
日期：2021-04-13
卷期号：143 (15): 1502-1512
被引量：10
标识
DOI：10.1161/circulationaha.120.050455
摘要
Background: TTN (Titin), the largest protein in humans, forms the molecular spring that spans half of the sarcomere to provide passive elasticity to the cardiomyocyte. Mutations that disrupt the TT...
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