抗氧化剂
体外
化学
细胞毒性T细胞
纳米颗粒
胶体金
核化学
组合化学
纳米技术
材料科学
生物化学
作者
S. P. Vinay,Udayabhanu,H.N. Sumedha,M. Shashank,Goli Nagaraju,N. Chandrasekhar
标识
DOI:10.1016/j.jsamd.2020.09.008
摘要
In the present study, we have follwed the hydrothermal path for the synthesis of gold nanoparticles (Au NPs) from the biomaterial Elaeocarpus ganitrus seeds extract, which is a rapid, eco-friendly, non-chemical way. The prepared NPs were thoroughly analysed by powder x-ray diffraction and high resolution transmission electron microscopy studies and were also tested for anticancer studies. Besides, the antioxidant, antibacterial and anticancer properties of Au NPs were studied. In vitro studies revealed the dose-dependent cytotoxic effect of Au NPs. The prepared nanoparticles showed good cytotoxic impact against a prostate cancer (PC-3) cells line. The evidences of the current study lead to the synthesis of novel and cost-effective drugs from Elaeocarpus ganitrus seeds extract by using the bio approach.
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