医学
低温消融
放射治疗
氩
CD8型
免疫系统
外科
内科学
烧蚀
免疫学
物理
原子物理学
作者
Zheng Zheng,Yingchun Zhao,Yonghui An,Na Li,Changwen Bo,Wenhua Ma,Ying Guo,Changpeng Zou,Bo Tian,Sujing Zhang
摘要
Our study aimed to investigate the clinical efficacy of argon-helium cryoablation and its effects on the immune function of patients with neck malignant tumours.Retrospective study.Single-institution academic tertiary care centre.Totally, 180 patients harbouring head and neck malignant tumours were divided into the argon-helium cryoablation group (n = 150) and the radiotherapy group (n = 50). The efficacy of the two groups was compared, and the immune function was observed.The short-term clinical effect of the argon-helium cryoablation group was significantly higher than that of the radiotherapy group (P < .05). After treatment, the CD3+, CD4+, CD8+ and CD4+/CD8+ of the argon-helium cryoablation group were significantly better than those of the radiotherapy group (P < .001). The results of TNF-α, IL-1 β and CRP in the argon-helium cryoablation group were significantly better than that in the radiotherapy group (P < .001).Argon-helium cryoablation could effectively improve the immune function, 5-year survival rate and local remission rate.
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