医学
2型糖尿病
代谢综合征
血脂异常
围手术期
肥胖
减肥
糖尿病
观察研究
内科学
外科
重症监护医学
内分泌学
作者
Zubaidah Nor Hanipah,Philip R. Schauer
标识
DOI:10.1146/annurev-med-053117-123246
摘要
Metabolic surgery is increasingly becoming recognized as a more effective treatment for patients with type 2 diabetes (T2D) and obesity as compared to lifestyle modification and medical management alone. Both observational studies and clinical trials have shown metabolic surgery to result in sustained weight loss (20-30%), T2D remission rates ranging from 23% to 60%, and improvement in cardiovascular risk factors such as hypertension and dyslipidemia. Metabolic surgery is cost-effective and relatively safe, with perioperative risks and mortality comparable to low-risk procedures such as cholecystectomy, hysterectomy, and appendectomy. International diabetes and medical organizations have endorsed metabolic surgery as a standard treatment for T2D with obesity.
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