Application of Poly(N-isopropylacrylamide) As Thermosensitive Smart Materials

Abstract Drug delivery systems refer to a technical system capable of comprehensively regulating the distribution of drugs in a living body in terms of time, space and dose. As thermosensitive smart materials, Poly(N-isopropylacrylamide) (PNIPAM) is an ideal treatment platform for the development of drug delivery systems. This article focuses on the application of various thermally sensitive smart materials such as nanoparticles, nanofibers, hydrogels, and self-assembled micelles in drug delivery systems prepared by PNIPAM in recent years. The future development of PNIPAM thermosensitive smart materials is also discussed.