I2‐Promoted [3+2] Cyclization of Thiocarbamates with Enaminones: a Protocol for the Synthesis of Polysubstituted Thiazol‐2(3H)‐ones

Abstract An I 2 ‐promoted [3+2] cyclization reaction between thiocarbamates with enaminones has been developed for the synthesis of thiazol‐2(3 H )‐one derivatives. This protocol involves C−S and C−N bond formation and exhibits good functional group tolerance. The reaction proceeded well at room temperature and provided up to 98% yield of the desired products.