光学相干层析成像
脉络膜
浆液性液体
医学
脉络膜新生血管
荧光血管造影
眼科
眼底(子宫)
病变
吲哚青绿
病理
视力
视网膜
光学
物理
作者
Saarang Hansraj,Jay Chhablani,Umesh Chandra Behera,Sagarika Patyal,Raja Narayanan,Niroj Kumar Sahoo
标识
DOI:10.1016/j.ajo.2024.02.025
摘要
Abstract
Purpose
To describe a potential biomarker termed as inner choroidal fibrosis in cases of chronic central serous chorioretinopathy presenting to a tertiary referral center. Design
Observational case series. Methods
Five eyes of four patients with chronic central serous chorioretinopathy, were noted to have a grey-white subretinal lesion in the macula, which was analyzed with multimodal imaging. Results
It was seen that the lesions were hypofluorescent on autofluorescence, fundus fluorescein angiography and indocyanine angiography. In all cases a characteristic heterogeneous, hyper-reflective lesion in the inner choroid was seen on optical coherence tomography (OCT), corresponding to the white subretinal lesions. The lesion was distinct from the adjacent choroid, with greater reflectivity and greater thickness than the adjacent compressed choroidal vasculature. The dilated outer pachyvessels were pushed outwards or sideways in all cases. On OCT-angiography, the corresponding lesion showed flow void areas. We have termed this zone of inner choroidal hyper-reflectivity as "inner choroidal fibrosis". Upon analyzing the clinical course, three of the patients had a history of choroidal neovascularization. The contralateral eye in two of these three patients also developed choroidal neovascularization. Three of the eyes had an overlying focal choroidal excavation. Conclusion
We report a potential biomarker of central serous chorioretinopathy termed as "inner choroidal fibrosis" in four cases of chronic CSCR. It can best be identified on enhanced depth or swept source OCT as a region of heterogeneous hyper-reflectivity in the inner choroid. This fibrosis could be regarded as a degenerative process secondary to more severe disease in the past.
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