[Research progress on the histological scoring system for nonalcoholic fatty liver disease].

Non-alcoholic fatty liver disease (NAFLD) has replaced chronic hepatitis B as the most common chronic liver disease in China and has now been renamed metabolic dysfunction-associated fatty liver disease (MAFLD). The Brunt, the American NASH Clinical Research Network (NASH-CRN), the European Steatosis, Activity, and Fibrosis/Fatty Liver Inhibition of Progression (SAF/FLIP), and the Pediatric NAFLD are currently the four semi-quantitative grading systems for histological evaluation. This paper reviews these four scoring systems for the clinical selection of appropriate systems for diagnosis and prognosis assessment. This article is a review, and in order to coordinate the evaluation criteria of various scoring systems, the old name "NAFLD" is used.非酒精性脂肪性肝病（NAFLD）已取代慢性乙型肝炎成为我国最常见的慢性肝病，现已更名为代谢相关脂肪性肝病（MAFLD），目前对其进行组织学评价的半定量评分系统主要有4种，包括Brunt评分系统、美国非酒精性脂肪性肝炎临床研究网络（NASH-CRN）评分系统、欧洲抑制脂肪肝进展小组（FLIP）提出的脂肪变性活动度纤维化（SAF）评分系统（SAF/FLIP）和儿童NAFLD组织学评分系统。现对这4种评分系统进行综述，以供临床医师选择合适的系统进行诊断和预后评估。该文为综述性论文，为协调各评分系统的评价标准，遂使用旧称"NAFLD"。.