Correlation of Serum Uric Acid and Lipid Profile in Patients with Type 2 Diabetes Mellitus.

医学 尿酸 内科学 糖尿病 甘油三酯 内分泌学 血脂谱 高密度脂蛋白 2型糖尿病 风险因素 血脂 静脉血 胆固醇 2型糖尿病
作者
Pragya Malla,Madhav Khanal,Asmita Pokhrel,Birendra Kumar Sah,S. Pathak,A. Subedi,Srijana Sapkota
出处
期刊:PubMed 卷期号:21 (1): 170-174
标识
DOI:10.33314/jnhrc.v21i1.4781
摘要

Diabetes complication poses a new challenge in Nepal as the disease is becoming endemic. Identifying risk factor for diabetes can be an essential step in preventing complication related to diabetes. Abnormal Uric acid and lipid profile are the important risk indicators of diabetes mellitus complications, so the study was done to know the association between uric acid and lipid profile in type 2 diabetes.A cross-sectional study was done from 118 patients with type 2 diabetes mellitus visiting Nepal Medical College and Teaching Hospital. Three ml of venous blood was analyzed for fasting blood glucose, uric acid, and lipid profile. Correlational analysis was done between fasting blood glucose with triglycerides, high density lipoproteins and uric acid.A significant positive correlation between fasting blood glucose and triglyceride (r =.211, p = .022) was found in diabetic. There was significant negative correlation of fasting blood glucose with uric acid (r = -.196, p =.034) and high-density lipoprotein cholesterol (r = -.181, p = .049). Uric acid was also found to have significant positive correlation with triglyceride (r = .235, p = .010) and negative correlation with high density lipoprotein cholesterol (r = -.420, p = .000).Negative correlation of serum uric acid with fasting blood glucose and high-density lipoprotein and positive correlation with triglycerides suggests a possible connection of uric acid as a risk factor for diabetes.
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