医学
抗蛇毒血清
毒蛇
血栓形成
环境化
蝰蛇科
重症监护医学
心理干预
外科
皮肤病科
生态学
精神科
毒液
生物
作者
Subramanian Senthilkumaran,Sasikumar Sampath,Stephen W. Miller,José R. Almeida,Jarred Williams,Harry F. Williams,Ponniah Thirumalaikolundusubramanian,Ketan Patel,Sakthivel Vaiyapuri
出处
期刊:Toxicon
[Elsevier]
日期:2023-09-07
卷期号:234: 107284-107284
标识
DOI:10.1016/j.toxicon.2023.107284
摘要
Snakebite envenoming (SBE) is common in rural communities living in tropical regions that often have fragile and/or overwhelmed healthcare systems. The complex scenarios around SBE lead to a high number of deaths, disabilities, and long-term consequences in patients. Russell's viper (Daboia russelii) is one of the most medically important snake species in India, which causes devastating pathological conditions characterised by a wide range of clinical manifestations. This broad spectrum of symptoms requires additional therapeutic interventions beyond the classical antivenom administration. Hence, positive outcomes for patients affected by SBE can be achieved with a better understanding of previous experiences describing clinical manifestations and various therapeutic interventions including for rare and underreported conditions. Here, we report an SBE victim who developed partial segmental thrombosis in the corpus cavernosum following Russell's viper envenomation and its diagnostic and treatment approaches. The patients received 180 ml of antivenom to resolve the abnormalities in their haematological parameters. Despite antivenom treatment, they developed severe pain in their genital region, and subsequent ultrasound and magnetic resonance imaging confirmed segmental thrombosis in the corpus cavernosum, which required supportive measures. The treatment using low molecular weight heparin, rivaroxaban and non-steroidal anti-inflammatory drugs resolved segmental thrombosis. In conclusion, this case report exemplifies the development of a rare segmental thrombosis in corpus cavernosum and how the medical, scientific, and general community can benefit from documenting clinical manifestations, medically relevant insights into patient care and the management of underreported complications.
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