彭布罗利珠单抗
肿瘤科
三阴性乳腺癌
医学
乳腺癌
内科学
阶段(地层学)
癌症
生物
免疫疗法
古生物学
作者
Peter Schmid,Javier Cortes,Rebecca Dent,Heather L. McArthur,Lajos Pusztai,Sherko Kümmel,Carsten Denkert,Yeon Hee Park,Rina Hui,Nadia Harbeck,Masato Takahashi,Seock‐Ah Im,Michael Untch,Peter A. Fasching,Marie‐Ange Mouret‐Reynier,Theodoros Foukakis,Marta Ferreira,Fátima Cardoso,Xuan Zhou,Vassiliki Karantza
标识
DOI:10.1056/nejmoa2409932
摘要
Neoadjuvant pembrolizumab plus chemotherapy followed by adjuvant pembrolizumab resulted in a significant improvement, as compared with neoadjuvant chemotherapy alone, in overall survival among patients with early-stage triple-negative breast cancer. (Funded by Merck Sharp and Dohme, a subsidiary of Merck [Rahway, NJ]; KEYNOTE-522 ClinicalTrials.gov number, NCT03036488.).
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