纳米囊
药物输送
纳米载体
纳米技术
纳米颗粒
固体脂质纳米粒
肺表面活性物质
药品
化学
尼奥体
材料科学
药理学
生物化学
医学
小泡
膜
作者
Parveen Kumar,Nishant Yadav,Benu Chaudhary,Srikant Umakanthan,Vijay Kumar Chattu,Imran Kazmi,Fahad A. Al‐Abbasi,Sami I. Alzarea,Obaid Afzal,Abdulmalik Saleh Alfawaz Altamimi,Gaurav Gupta,Madan M. Gupta
出处
期刊:Current Pharmaceutical Biotechnology
[Bentham Science]
日期:2024-02-01
卷期号:25 (3): 268-284
被引量:5
标识
DOI:10.2174/1389201024666230523114350
摘要
Abstract: Nanocapsules are polymeric nanoparticles encased in a polymeric coating composed of a predominantly non-ionic surfactant, macromolecules, phospholipids, and an oil core. Lipophilic drugs have been entrapped using various nanocarriers, including lipid cores, likely lipid nanocapsules, solid lipid nanoparticles, and others. A phase inversion temperature approach is used to create lipid nanocapsules. The PEG (polyethyleneglycol) is primarily utilised to produce nanocapsules and is a critical parameter influencing capsule residence time. With their broad drug-loading features, lipid nanocapsules have a distinct advantage in drug delivery systems, such as the capacity to encapsulate hydrophilic or lipophilic pharmaceuticals. Lipid nanocapsules, as detailed in this review, are surface modified, contain target-specific patterns, and have stable physical and chemical properties. Furthermore, lipid nanocapsules have target-specific delivery and are commonly employed as a marker in the diagnosis of numerous illnesses. This review focuses on nanocapsule synthesis, characterisation, and application, which will help understand the unique features of nanocapsules and their application in drug delivery systems.
科研通智能强力驱动
Strongly Powered by AbleSci AI