多巴胺能
多巴胺
调解人
睡眠(系统调用)
果蝇属(亚属)
神经肽
感觉系统
生物
细胞生物学
内科学
内分泌学
神经科学
基因
生物化学
计算机科学
医学
受体
操作系统
作者
Zita Carvalho-Santos,Carlos Ribeiro
标识
DOI:10.1016/j.cmet.2023.04.001
摘要
A recent study by Titos et al. in Cell shows that protein-rich diets are strong modulators of sleep depth in Drosophila and identifies the gut-secreted neuropeptide CCHa1 as the mediator of this effect. In the brain, CCHa1 controls dopamine release from a small set of neurons, thereby modulating arousability by integrating internal state with sensory information. A recent study by Titos et al. in Cell shows that protein-rich diets are strong modulators of sleep depth in Drosophila and identifies the gut-secreted neuropeptide CCHa1 as the mediator of this effect. In the brain, CCHa1 controls dopamine release from a small set of neurons, thereby modulating arousability by integrating internal state with sensory information. A gut-secreted peptide suppresses arousability from sleepTitos et al.CellMarch 22, 2023In BriefDietary proteins can promote sensory disconnect during sleep; in flies, the effect is mediated by a gut-secreted peptide which signals to dopaminergic neurons in the brain. Full-Text PDF
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