Remimazolam and Ciprofol: More Research Is Needed but Ask the Right Questions and Perhaps Aim Higher

City dwellers of a certain age will recall lengthy waits for a bus followed eventually by the arrival of three on the same route driving nose-to-tail. So it is with intravenous hypnotics. Since the discovery of propofol, it has been a long wait. Now we have remimazolam (two different versions) launched worldwide, ciprofol in phase 3 studies, and several other candidates in the early stages of development.