水分
体外
临床试验
医学
材料科学
生物医学工程
复合材料
内科学
生物
生物化学
作者
Sang Gyu Lee,Nuu Nai Nguyen,Young In Lee,Inhee Jung,In Ah Kim,Hyun‐Sook Jang,Hoyeon Shin,JuHee Lee
摘要
Skin aging is driven by a combination of internal and external mechanisms, with ultraviolet (UV) radiation being a prominent external factor contributing to photoaging. Photoaging manifests through several signs, including decreased skin hydration, diminished elasticity, coarse wrinkles, and dyspigmentation. Cacao beans, known for their flavonoids and polyphenols, offer potential anti-aging benefits. To explore this, we conducted a study using both in vitro experiments and clinical trials. Our results demonstrated that cacao powder significantly improved skin hydration and moisture retention in both experimental settings. Specifically, in UVB-damaged human dermal fibroblasts (HDFs) and H
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