谵妄
医学
重症监护室
重症监护医学
急诊医学
急症护理
梅德林
风险评估
医疗保健
政治学
计算机安全
计算机科学
经济增长
经济
法学
作者
Guy Stanley,Angus R.J. Barber,Aoife M. O'Brien,Cheryl Hamill,Glenn Boardman,Cody C. Frear,Dale W. Edgar,Hannah Seymour,Fiona Wood
出处
期刊:Burns
[Elsevier]
日期:2022-08-01
卷期号:48 (5): 1040-1054
被引量:3
标识
DOI:10.1016/j.burns.2022.05.023
摘要
Delirium is a potentially modifiable, acutely altered mental state, commonly characterised as a hospital-acquired complication. Studies of adult inpatients with acute burns with and without delirium identify causative risks related to the injury or treatment and outcomes related to the patient and healthcare system. We compare patients with and without delirium, providing a high-level quantitative synthesis of delirium risks and outcomes to inform guidelines and future research. A systematic review, meta-analysis and GRADE evaluation of risks and outcomes associated with delirium in adults with acute burns was conducted using PRISMA guidelines and PROSPERO protocol CRD42021283055. The Newcastle-Ottawa Scale was used to assess quality. Investigators reviewed ten studies. ASA score ≥ 3, Total Body Surface Area Percentage (TBSA)> 10%, surgery done, ICU admission, hospital and also Intensive Care Unit (ICU) lengths of stay all had statistically significant associations with delirium, with low-very low certainty on GRADE evaluation. Limitations were heterogeneous studies, review methodology and study bias. Delirium represents a significant risk to comorbid patients with burns that are hospitalised, receive ICU care, and surgery. Further research is indicated to precisely categorise delirium along the clinical journey to identify modifiable factors, prevention, and proactive therapy.
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