AB0986 RISK OF SARCOPENIA IN THE WOMEN WITH OSTEOARTHRITIS

Background Recently, physicians all over the world have been focusing on the relationship between sarcopenia and osteoarthritis (OA) [1, 2]. This connection is considered from different positions: as coexisting conditions, sarcopenia as a risk factor for the progression of OA, or OA as a risk factor for sarcopenia. Objectives The aim of this study was to determine the risk of sarcopenia (according to the SARC-F Questionnaire) and the level of probable sarcopenia in Ukrainian women with (hip and knee) OA. Methods The study included 271 women aged 50-84 years old (mean age 65.6 ±8.0 years, mean height 162.2±5.6, mean body weight 76.7±14.2, mean BMI 29.1±5.1). All subjects were divided into 2 groups: the group of healthy women (group I, n=176), a group of patients with hip or knee osteoarthritis (OA) (group II, n=95). The risk of sarcopenia was determined by the SARC-F Questionnaire. The probable sarcopenia was determined due to muscles strength (handgrip strength using spring hand dynamometer ≤ 16(kg)) and physical performance (5-time chair stand test > 15 s), the fall risk – by Desmond Fall Risk Questionnaires and function – according to the assessment of IADL scale. Results In 20.3% of females without musculoskeletal pathology and in 34.7% of women with OA was detected high risk of sarcopenia. The probable sarcopenia was practically 2 times higher in patients with OA and was equal to 42.1% compared to 21.5% in healthy women. According to the Desmond Fall Risk Questionnaire, 27.5% of healthy subjects and 49.3% with OA had increased fall risk. Low function (according to the assessment of the IADL scale) was detected in 36.4% of females without pathology of the musculoskeletal system and in 57.2% of women with OA. Conclusion Our results demonstrated that the incidence of probable sarcopenia was 2 times higher in women with hip and knee OA, as well as the risk of sarcopenia – 34.7%, compared to healthy subjects – 20.3%. Also, the risk of falls and the need for outside help were higher in patients with hip and knee OA but their function (by IADL scale) was significantly lower. References [1]Amirthalingam H., Cicuttini F. M., Wang Y. et al. (2019). Association between sarcopenia and osteoarthritis-related knee structural changes: a systematic review. Osteoarthritis and Cartilage, 27, S472. doi:10.1016/j.joca.2019.02.515. [2]Jin W. S., Choi E. J., Lee S. Y. et al. (2017). Relationships among Obesity, Sarcopenia, and Osteoarthritis in the Elderly. Journal of Obesity & Metabolic Syndrome, 26(1), 36–44. doi:10.7570/jomes.2017.26.1.36. Disclosure of Interests None declared