Effect of suprainguinal fascia iliaca compartment block on postoperative opioid consumption and functional recovery in posterolateral-approached total hip arthroplasty: a single-blind randomized controlled trial

医学 罗哌卡因 麻醉 直立生命体征 恶心 吗啡 随机对照试验 外科 关节置换术 血压 内科学
作者
Michele Carella,F. Michael Beck,Nicolas Piette,Sébastien Denys,W. S. Kŭrth,Jean-Pierre Lecoq,Vincent Bonhomme
出处
期刊:Regional Anesthesia and Pain Medicine [BMJ]
卷期号:47 (9): 547-553 被引量:15
标识
DOI:10.1136/rapm-2021-103427
摘要

Introduction Posterolateral-approached total hip arthroplasty (PLTHA) is followed by moderate to severe postoperative pain. Suprainguinal fascia iliaca compartment block (SFICB) has been proposed as a promising analgesia technique. Methods Data from 86 patients scheduled for PLTHA with spinal anesthesia were analyzed in this prospective randomized controlled trial. Patients were randomly divided into two groups of 43 patients each. As opposed to the control group (group C), ropivacaine group (group R) received additional SFICB using 40 mL of 0.375% ropivacaine. As primary endpoint, blind observers noted total morphine consumption at postoperative 48 hours. Secondary endpoints were pain at rest and mobilization on 0–10 Numeric Rating Scale (rest and dynamic NRS) at fixed time points (1 hour and 6 hours after surgery, and at day 1 and day 2 at 8:00, 13:00 and 18:00 hours), walking performance at day 1 and day 2; postoperative complications including morphine-related side effects or orthostatic intolerance symptoms such as dizziness, nausea, blurred vision or vasovagal syncope. Results A 48-hour morphine consumption (mg; median (IQR)) was significantly lower in group R than in group C (11 (8.5–15.5)) vs 26 (21–33.5), p<0001), as well as incidence of morphine-related side effects such as nausea at day 1 (p=0.04) and day 2 (p<0.01). Rest and dynamic NRS were globally significantly lower in group R than in group C (p<0.01). Group R showed less orthostatic intolerance at day 1 (p<0.001) and day 2 (p<0.01) and better functional walking performance at day 1 (<0.001) and day 2 (<0.001). Discussion In PLTHA, SFICB provides opioid sparing, improved postoperative pain control, and enhanced functional recovery. Trial registration number NCT04574479 .
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
1秒前
snowpie完成签到 ,获得积分10
1秒前
fufu完成签到,获得积分10
1秒前
1秒前
嗯哼应助西番雅采纳,获得10
2秒前
2秒前
4秒前
4秒前
redamancy发布了新的文献求助10
6秒前
鲸鱼发布了新的文献求助10
6秒前
7秒前
hadern发布了新的文献求助10
7秒前
bird完成签到 ,获得积分10
9秒前
甜蜜的振家完成签到,获得积分10
11秒前
11秒前
11秒前
大个应助hadern采纳,获得10
12秒前
转身风飘去完成签到,获得积分10
15秒前
15秒前
还单身的若蕊完成签到,获得积分10
15秒前
结实的逍遥完成签到,获得积分10
16秒前
龙在天发布了新的文献求助10
16秒前
混沌完成签到,获得积分10
17秒前
隐形曼青应助xjr采纳,获得10
19秒前
19秒前
20秒前
20秒前
22秒前
Nemo完成签到,获得积分20
22秒前
过时的不评完成签到,获得积分10
24秒前
年轻上线发布了新的文献求助10
25秒前
舒心的大有关注了科研通微信公众号
25秒前
含蓄宛海完成签到,获得积分10
26秒前
阳光he完成签到,获得积分10
28秒前
31秒前
Rchy完成签到,获得积分10
31秒前
orixero应助博修采纳,获得10
31秒前
左右兮完成签到,获得积分10
32秒前
34秒前
高分求助中
Rock-Forming Minerals, Volume 3C, Sheet Silicates: Clay Minerals 2000
The late Devonian Standard Conodont Zonation 2000
Nickel superalloy market size, share, growth, trends, and forecast 2023-2030 2000
The Lali Section: An Excellent Reference Section for Upper - Devonian in South China 1500
Very-high-order BVD Schemes Using β-variable THINC Method 910
Mantiden: Faszinierende Lauerjäger Faszinierende Lauerjäger 800
PraxisRatgeber: Mantiden: Faszinierende Lauerjäger 800
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3262544
求助须知:如何正确求助?哪些是违规求助? 2903181
关于积分的说明 8324328
捐赠科研通 2573216
什么是DOI,文献DOI怎么找? 1398126
科研通“疑难数据库(出版商)”最低求助积分说明 654018
邀请新用户注册赠送积分活动 632623