镓
材料科学
纳米技术
液态金属
生物相容性
微流控
纳米颗粒
生物医学工程
冶金
医学
作者
Ruixue Liu,Linji Gong,Xianyu Zhu,Shuang Zhu,Xiaochen Wu,Tingyu Xue,Liang Yan,Jiangfeng Du,Zhanjun Gu
标识
DOI:10.1002/adhm.202102584
摘要
enriched tumor physiological microenvironment. Due to the metallic nature and high density, EGaIn can increase the generation of reactive oxygen species under the irradiation of X-ray, which can not only directly promote DNA damage and cell apoptosis, but also show an efficient tumor inhibition rate in vivo. Moreover, EGaIn@Alg NPs hold good performance as computed tomography (CT) and photoacoustic tomography (PAT) imaging contrast agents. This work provides an alternative nanotechnology strategy for tumor radiosensitization and also enlarges the biomedical application of gallium-based LM.
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