Immune Cell Metabolism and Function

Immune cells are highly dynamic by nature and rely on metabolism to adapt to different conditions. Many recent studies have shown the importance of immune cells and their metabolism in the pathogenesis of many diseases. Cellular metabolism acts as a guiding force to regulate immune cell activation, differentiation, and cellular behavior, thus regulating the extent of the immune response. Here in this chapter, we have discussed different metabolic signatures and pathways that control the activation status of immune cells and how the change in the metabolic status affects the immune response, disease pathobiology, and homeostasis especially in cancer.