Daridorexant for insomnia disorder

Insomnia disorder is defined by difficulties initiating or maintaining sleep, or both, resulting in substantial daytime dysfunction.1 In industrialised countries, 5–10% of the general population have the disorder.2 According to the guidelines of the American College of Physicians3 and the European Sleep Research Society,4 the first-line treatment for the disorder is cognitive behavioural therapy for insomnia (CBT-I). This treatment is safe and effective but not widely available.1