Histiocytic medullary reticulosis

Abstract The case presented fulfills the clinical and morphologic requirements of histiocytic medullary reticulosis as laid down by Bodley Scott and Robb-Smith [1]. This invariably and apparently rapidly fatal disease of adults is characterized morphologically by a diffuse proliferation of phagocytic histiocytes and their precursors in lymph nodes, spleen, liver, bone marrow and other organs. The striking erythrophagocytosis, particularly in the spleen, is diagnostic. Wasting, fever, moderate lymph node enlargement, hepatosplenomegaly, hypersplenism and icterus are found.