A Metal‐Free Sulfenylation and Bromosulfenylation of Indoles: Controllable Synthesis of 3‐Arylthioindoles and 2‐Bromo‐3‐arylthioindoles

Abstract An efficient metal‐free sulfenylation of indoles with disulfides has been developed, leading to 3‐arylthioindoles in moderate to excellent yields. Furthermore, bromosulfenylation of indoles with disulfides has been realized for the first time providing a new family of 2‐bromo‐3‐arylthioindole derivatives in good yield by the one‐pot construction of CS and CBr bonds. It is noteworthy that the system enables the use of both the RS moieties in RSSR and shows a broad functional group tolerance.