SYNTHESIS OFN-SUBSTITUTED PYRROLO[3,4-b]INDOLES FROM 2,3-DIMETHYLINDOLE

ABSTRACT Pyrrolo[3,4-b]indoles 8 are conveniently synthesized from 2,3-dimethylindole (4) in four steps, the last of which is DDQ oxidation of dihydropyrrolo[3,4-b]indoles 7 (85–98% yield). Keywords: Pyrrolo[3,4-b]indolesIndole-2,3-quinodimethaneDDQ oxidation ACKNOWLEDGMENTS This investigation was supported by the National Institutes of Health (GM58601), for which support we are grateful.