Noncontact Infrared Meibography to Document Age-Related Changes of the Meibomian Glands in a Normal Population

睑板腺 眼睑 医学 希默试验 眼科 人口 干眼症 环境卫生
作者
Reiko Arita,Kouzo Itoh,Kenji Inoue,Shiro Amano
出处
期刊:Ophthalmology [Elsevier]
卷期号:115 (5): 911-915 被引量:662
标识
DOI:10.1016/j.ophtha.2007.06.031
摘要

To examine the morphologic changes in meibomian glands associated with aging and gender using a novel meibography system and to assess their relation with slit-lamp findings regarding eyelid and tear film function in a normal population.Cross-sectional observation case series.Two hundred thirty-six healthy volunteers (114 men, 122 women; mean age+/-standard deviation, 41.2+/-23.1 years; range, 4-98 years).The upper and lower eyelids were turned over and the meibomian glands were observed using the noncontact meibography system, which consisted of a slit lamp equipped with an infrared charge-coupled device video camera and an infrared transmitting filter. A transilluminating light probe was not necessary. Partial or complete loss of the meibomian glands was scored for each eyelid from grade 0 (no loss of meibomian glands) through grade 3 (the lost area was more than two thirds of the total meibomian gland area). The tear film break-up time (BUT) was measured and tear film production was evaluated by Schirmer test.Score of meibomian gland changes (meiboscore), tear film BUT, and Schirmer test value.Using the meibography system, clear images of the meibomian glands were obtained in all subjects, including children. There were significant positive correlations between age and meiboscore in the entire subject population (R = 0.428; P<0.0001), as well as in males (R = 0.462; P<0.0001) and females (R = 0.418; P<0.0001). There were significant negative correlations between age and tear film BUT (R = -0.153; P = 0.019) and the Schirmer test value (R = -0.289; P<0.0001). The meiboscore was significantly positively correlated with the lid margin abnormality score (R = 0.359; P<0.0001).The noncontact meibography system is a useful, quick, and patient-friendly method for obtaining information on the meibomian gland structure. Using this method, the authors found that changes in meibomian glands increase with age.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
hhhh发布了新的文献求助10
1秒前
风再起时应助QI采纳,获得20
1秒前
liuxuwei发布了新的文献求助10
1秒前
1秒前
隐形曼青应助Rainay采纳,获得10
1秒前
2秒前
2秒前
大模型应助罗静采纳,获得10
3秒前
4秒前
5秒前
研友_8y2G0L发布了新的文献求助10
5秒前
LKSkywalker发布了新的文献求助10
5秒前
CYP完成签到 ,获得积分10
6秒前
陆磊磊完成签到,获得积分10
7秒前
liuxuwei完成签到,获得积分10
7秒前
fuguier发布了新的文献求助10
7秒前
赘婿应助扶桑采纳,获得10
7秒前
香蕉觅云应助活力尔竹采纳,获得10
8秒前
qiqi发布了新的文献求助10
8秒前
XD发布了新的文献求助10
9秒前
YL发布了新的文献求助10
9秒前
9秒前
黄花发布了新的文献求助10
10秒前
qifeng完成签到,获得积分10
10秒前
庞扬发布了新的文献求助10
10秒前
周斌发布了新的文献求助10
11秒前
梦魇发布了新的文献求助10
13秒前
13秒前
酒石酸发布了新的文献求助10
14秒前
markerfxq发布了新的文献求助10
14秒前
深情安青应助传统的香菇采纳,获得30
14秒前
JamesPei应助研友_8y2G0L采纳,获得10
14秒前
无为完成签到,获得积分10
15秒前
林夕夕完成签到,获得积分10
15秒前
嗖嗖完成签到,获得积分10
16秒前
Foremelon发布了新的文献求助10
16秒前
16秒前
稳重的青丝完成签到,获得积分10
16秒前
16秒前
领导范儿应助纯真硬币采纳,获得10
16秒前
高分求助中
The late Devonian Standard Conodont Zonation 2000
Nickel superalloy market size, share, growth, trends, and forecast 2023-2030 2000
The Lali Section: An Excellent Reference Section for Upper - Devonian in South China 1500
Very-high-order BVD Schemes Using β-variable THINC Method 870
Mantiden: Faszinierende Lauerjäger Faszinierende Lauerjäger 800
PraxisRatgeber: Mantiden: Faszinierende Lauerjäger 800
Fundamentals of Dispersed Multiphase Flows 500
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3254532
求助须知:如何正确求助?哪些是违规求助? 2896743
关于积分的说明 8294237
捐赠科研通 2565722
什么是DOI,文献DOI怎么找? 1393275
科研通“疑难数据库(出版商)”最低求助积分说明 652462
邀请新用户注册赠送积分活动 630026