Palladium-catalyzed oxidative amidation of quinoxalin-2(1H)-ones with acetonitrile: a highly efficient strategy toward 3-amidated quinoxalin-2(1H)-ones

An efficient protocol for the synthesis of 3-amidated quinoxalin-2(1H)-ones has been developed via a palladium-catalyzed cross-coupling reaction of quinoxalin-2(1H)-ones with acetonitrile.