Chemical constituents from stems of Aquilaria sinensis

OBJECTIVE: To study the constituents from the stems of Aquilaria sinensis. METHOD: The chemical constituents were isolated by various column chromatographic methods. The structures were identified by spectral analysis including NMR and MS data. RESULT: Sixteen compounds were isolated and identified as threo-buddlenol C (1), thero-ficusesquilignan A (2), erythro-buddlenol C (3), (+/-) buddlenol D (4), (-) medioresinol (5), (-) pinoresinol (6), 5'-methoxy lariciresinol (7), erythro-guaiacylglycerol-beta-coniferyl ether (8), thero-guaiacylglycerol-beta-coniferyl ether (9), herpetin (10), (+) syringaresinol (11), curuilignan (12), ciwujiatone (13), coniferyl alcohol (14), 3, 4, 5-trimethoxyphenol (15) and cucurbitacin (16). CONCLUSION: All the compounds, except for 11-13 were obtained from A. sinensis for the first time.