Effects of exercise training on immunological factors in kidney transplant recipients; a randomized controlled trial

医学 免疫系统 FOXP3型 有氧运动 内科学 肾移植 免疫学 物理疗法 肾移植
作者
Nazi Hemmati,Sohrab Kazemi,Narges Jamshidian Tehrani,Jamshid Roozbeh,Maryam Koushkie Jahromi,Mohsen Salesi,Meghdad Abdollahpour‐Alitappeh,Mohammad Hossein Karimi
出处
期刊:Research in Sports Medicine [Taylor & Francis]
卷期号:30 (1): 80-91 被引量:10
标识
DOI:10.1080/15438627.2021.1906671
摘要

The purpose of this study was to investigate the effects of a 12 week exercise training on the immune system of kidney transplant recipients. 23 kidney transplant recipients were randomly divided into two groups including control (n = 10) and training (n =13) groups. The training groups participated in the training for 10 weeks (three days a week; each day 60-90 minutes). The control group performed no regular exercise during this time. The blood samples were taken before and after 12 weeks. ELISA and Real-time PCR were used to evaluate cytokine profiles, including TNF-a, IL-6, IL-4, IL-31 and IL-35 as well as T-bet, GATA-3, RORYt and FOXP3, respectively. Finally, the data were analyzed, using paired T-test. ELISA results showed decreased levels of TNF- α, increased levels of IL-6 and no significant differences in the IL-35, IL-31 and IL-4 levels in the training group in comparison to the control group. Gene expression profiles showed significantly increased expression of T-bet and no changes in the GATA-3, RORYt and FOXP3 levels. According to these results, a moderate exercise including aerobic and resistance training could inhibit inflammatory cytokines and have beneficial effects on the immune system, but this issue needs further research.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
1秒前
1秒前
2秒前
2秒前
赖晨靓完成签到 ,获得积分10
3秒前
zhangmeimei完成签到,获得积分10
3秒前
JTYJRTY发布了新的文献求助10
4秒前
在水一方应助学术悍匪采纳,获得10
5秒前
不钓鱼发布了新的文献求助10
5秒前
乐乐应助会飞的野马采纳,获得10
6秒前
梦溪发布了新的文献求助10
7秒前
overThat完成签到,获得积分10
7秒前
YamDaamCaa应助yiqi采纳,获得30
8秒前
彩色不评完成签到,获得积分10
9秒前
刀笔吏完成签到,获得积分10
11秒前
Hiker完成签到,获得积分10
12秒前
13秒前
科研通AI5应助xuchen采纳,获得10
14秒前
勤奋高丽发布了新的文献求助20
15秒前
15秒前
ecoli完成签到,获得积分20
17秒前
18秒前
likes发布了新的文献求助10
19秒前
学术悍匪发布了新的文献求助10
19秒前
村医完成签到,获得积分10
20秒前
村医发布了新的文献求助30
23秒前
lesyeuxdexx完成签到 ,获得积分10
23秒前
25秒前
科研通AI2S应助义气萝卜头采纳,获得10
25秒前
杨小六发布了新的文献求助10
26秒前
悦耳的亦旋完成签到,获得积分10
26秒前
量子星尘发布了新的文献求助10
27秒前
27秒前
29秒前
30秒前
scichu完成签到,获得积分10
32秒前
whh发布了新的文献求助10
32秒前
夹子方糖发布了新的文献求助10
32秒前
34秒前
34秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 700
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3976253
求助须知:如何正确求助?哪些是违规求助? 3520405
关于积分的说明 11203301
捐赠科研通 3257028
什么是DOI,文献DOI怎么找? 1798589
邀请新用户注册赠送积分活动 877755
科研通“疑难数据库(出版商)”最低求助积分说明 806521