Non-operative treatment for gastroduodenal ulcer perforation

Objective To study the curative effect of non-operative treatment for perforated gastroduodenal ulcer (PGDU) and indications range. Methods Under broad indications PDGU patients underwent non-surgical treatment according to the standard of clinical evaluation curative effect, then perforation causes were determined by the early gastroscopy after curative effect is up to standards. Results From January 2005 to October 2015 PGDU was diagnosed in 236 cases and treated non-operatively. 8 cases were converted to surgical treatment (3.4%). 228 cases were cured (96.6%) non-surgically. Among those 213 cases (93.4%) underwent gastroscopy to detexmine the cause during the same hospitalization. Complications developed in 6.8% selected cases. These was no septic shock nor death during the treatment. Conclusions Modern comprehensive non-surgical treatment is effective for most PGDU cases without serious complications, except for those with septic shock, severe intra abdominal infection and massive ascites. Key words: Peptic ulcer perforation; Combined modality therapy; Indications