Novel nanotechnological approaches for treatment of skin-aging

药剂师 皮肤老化 医学 纳米载体 纳米毒理学 化妆品 脂质体 尼奥体 化妆品 姜黄素 白藜芦醇 纳米技术 药理学 皮肤病科 病理 纳米颗粒 生物 材料科学 药品 小泡 遗传学
作者
Ashmita Sharma,Anurag Kuhad,Ranjana Bhandari
出处
期刊:Journal of Tissue Viability [Elsevier]
卷期号:31 (3): 374-386 被引量:31
标识
DOI:10.1016/j.jtv.2022.04.010
摘要

One of the essential organs and protective barricades, the skin, needs to be taken care of early. Skin is affected by several intrinsic and extrinsic factors, and despite their morphological and pathological differences, they have many molecular similarities. As of today, various mechanisms and theories have been recommended for aging, such as cellular anility, reduced proliferative tendency, reduction in length of telomere, mutations in DNA, theory of free radical generation, and many others. In today's society, skin health is often considered an important indicator of health, which has led to an increased demand for anti-aging products. However, numerous conventional cosmetics and phytocompounds (curcumin, Vitamin E, resveratrol) utilized in anti-aging products have inimical physical and chemical attributes, including insufficient chemical stability and inadequate skin penetration bound their effectuality after topical administration. So recently, new novel nanotechnological approaches for preventing skin aging, such as liposomes, niosomes, solid lipid nanoparticles, transferosomes, ethosomes, nanostructured lipid carriers, and carbon nanotubes, are being used. Hence, the field of cosmeceutical nanomaterials is rapidly evolving, and we can look forward to seeing a variety of innovative nanotechnology-based cosmetic products be a game-changer for this multi-million anti-aging cosmetic industry.

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