Uncoupling IL-2 Signals that Regulate T Cell Proliferation, Survival, and Fas-Mediated Activation-Induced Cell Death

受体 流式细胞术 突变体 生物 T细胞 细胞生物学 收回 分子生物学 免疫学 免疫系统 遗传学 基因 数学 纯数学
作者
Luk Van Parijs,Yosef Refaeli,James D. Lord,Brad H. Nelson,Abul K. Abbas,David Baltimore
出处
期刊:Immunity [Cell Press]
卷期号:30 (4): 611-611 被引量:22
标识
DOI:10.1016/j.immuni.2009.04.002
摘要

(Immunity 11, 281–288; September 1, 1999) The authors have agreed to retract this paper because of duplication of the flow cytometry dot plots in Figure 1C (labeled as WT and Δ355+8F) by the first author. This figure shows the reconstitution of mouse cells deficient in IL-2 receptor beta with various wild-type and mutant human IL-2 receptor beta chains. This data established the system used to test various properties of these receptor chains in the later work of the paper. This matter was investigated by the California Institute of Technology and the Office of Research Integrity at the United States Department of Human Services, which found the first author to be responsible for the scientific misconduct pertaining to the issue described here. The authors stand by the validity of the other figures and sincerely apologize for the inconvenience caused by this retraction. RETRACTED: Uncoupling IL-2 Signals that Regulate T Cell Proliferation, Survival, and Fas-Mediated Activation-Induced Cell DeathVan Parijs et al.ImmunitySeptember 01, 1999In BriefThis article has been retracted at the request of the authors. Please see Elsevier Policy on Article Withdrawal ( http://www.elsevier.com/locate/withdrawalpolicy ). Reason: The authors have agreed to retract the paper because of duplication of the flow cytometry dot plots in Figure 1C (labeled as WT and Δ355+8F) by the first author. This figure shows the reconstitution of mouse cells deficient in IL-2 receptor beta with various wild type and mutant human IL-2 receptor beta chains. This data established the system used to test various properties of these receptor chains in the later work of the paper. Full-Text PDF Open Archive

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