作者
Ferdinandos Skoulidis,Bob T. Li,Grace K. Dy,Timothy Price,Gerald S. Falchook,Jürgen Wolf,Antoîne Italiano,Martin Schüler,Hossein Borghaei,Fabrice Barlési,Terufumi Kato,Alessandra Curioni‐Fontecedro,Adrian G. Sacher,Alexander I. Spira,Suresh S. Ramalingam,Toshiaki Takahashi,Benjamin Besse,Abraham Anderson,Agnes Ang,Qui Tran,Omar Mather,Haby Henary,Gataree Ngarmchamnanrith,Gregory Friberg,Vamsidhar Velcheti,Ramaswamy Govindan
摘要
Sotorasib showed anticancer activity in patients with KRAS p.G12C–mutated advanced solid tumors in a phase 1 study, and particularly promising anticancer activity was observed in a subgroup of patients with non–small-cell lung cancer (NSCLC).