The Association Between Admission Anemia and Poststroke Depression

哈姆德 医学 红细胞压积 改良兰金量表 萧条(经济学) 逻辑回归 评定量表 脑卒中后抑郁 冲程(发动机) 物理疗法 贫血 内科学 缺血性中风 心理学 日常生活活动 宏观经济学 显著性差异 机械工程 发展心理学 缺血 工程类 经济
作者
Jianhua Cheng,Qiongzhang Wang,Xiaoqian Luan,Jie Zhu,Wenqian Feng,Guiqian Huang,Shasha Lin,Jincai He
出处
期刊:Journal of Nervous and Mental Disease [Lippincott Williams & Wilkins]
卷期号:209 (6): 421-425 被引量:3
标识
DOI:10.1097/nmd.0000000000001314
摘要

Poststroke depression (PSD) is the most frequent and important neuropsychiatric problem afflicting these patients. Anemia is common in many of these individuals presenting with acute stroke. This study determined whether there is a relationship between anemia on hospital admission and PSD. Two hundred eighty-four acute stroke patients were included in the study. Among them, there were 88 PSD patients, whereas another 196 were non-PSD patients. Clinical depression symptoms were diagnosed according to DSM-4 (Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition) criteria and a HAMD-17 (the 17-item Hamilton Depression Scale) score ≥8 at 1 month after stroke. In the PSD patients, 27.3% of them presented with anemia, whereas only 12.8% of the non-PSD patients had this condition. There was a negative correlation between hemoglobin level and HAMD-17 score in all patients. A binary logistic regression analysis revealed that anemia was independently associated with PSD after adjustment for sex, National Institutes of Health Stroke Scale scores, mRS (modified Rankin Scale) scores, BI (Barthel Index) scores, RBC (red blood cell), and hematocrit. In conclusion, anemia at admission is associated with PSD seen in these patients 1 month later. Therefore, anemia is a possible predictor of PSD.
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