塞库金单抗
医学
斑块性银屑病
银屑病
单克隆抗体
单克隆
白细胞介素
皮肤病科
伊克泽珠单抗
银屑病性关节炎
免疫学
抗体
白细胞介素17
细胞因子
作者
Kristian Reich,Debabrata Bandyopadhyay,Mark Lebwohl,Melinda Gooderham,Bruce Strober,Richard G. Langley,C. Paul,Dirk De Cuyper,Veerle Vanvoorden,Cynthia Madden,Christopher Cioffi,Luke Peterson,Andrew Blauvelt
标识
DOI：10.1056/nejmoa2102383
摘要
Bimekizumab is a monoclonal IgG1 antibody that selectively inhibits both interleukin-17A and interleukin-17F. The efficacy and safety of bimekizumab as compared with secukinumab, which selectively inhibits interleukin-17A alone, in patients with moderate-to-severe plaque psoriasis have not been extensively examined.
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