Abstract Aim To demonstrate the use of the Invisalign appliance in lower incisor extraction cases. Method Twelve patients, consecutively treated by the removal of a single lower incisor and Invisalign appliances, were selected from the author’s private practice. Pretreatment, treatment and post-treatment photographic records were obtained and are presented. Results All cases completed treatment, with a mean treatment time of 42 weeks. Fifty percent of the cases required a brief period of refinement (average six weeks) at the end of the initial projected treatment period. Conclusion The Invisalign appliance, in correctly diagnosed cases, with careful ‘ClinCheck’ set-ups and good clinical monitoring, can routinely produce satisfactory outcomes in patients who require the removal of a lower incisor.