斑马鱼
细胞生物学
生物
细胞器
细胞内
转基因
绿色荧光蛋白
模式生物
遗传学
基因
作者
Chong Pyo Choe,Seok‐Yong Choi,Yun Kee,Min Jung Kim,Seok-Hyung Kim,Yoonsung Lee,Hae‐Chul Park,Hyunju Ro
标识
DOI:10.1186/s42826-021-00103-2
摘要
Abstract Since its debut in the biomedical research fields in 1981, zebrafish have been used as a vertebrate model organism in more than 40,000 biomedical research studies. Especially useful are zebrafish lines expressing fluorescent proteins in a molecule, intracellular organelle, cell or tissue specific manner because they allow the visualization and tracking of molecules, intracellular organelles, cells or tissues of interest in real time and in vivo. In this review, we summarize representative transgenic fluorescent zebrafish lines that have revolutionized biomedical research on signal transduction, the craniofacial skeletal system, the hematopoietic system, the nervous system, the urogenital system, the digestive system and intracellular organelles.
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