The complete DNA sequence of yeast chromosome III

遗传学基因染色体生物打开阅读框序列（生物学）酿酒酵母 DNA 酵母 DNA测序肽序列

作者

Stephen G. Oliver,Quirina J. M. Van Der Aart,M. L. Agostoni-Carbone,Michel Aigle,Lilia Alberghina,Despina Alexandraki,Gerhard Antoine,Rashida Anwar,Juan P. G. Ballesta,Paule Bénit,Gilbert Berben,Elisabetta Bergantino,Nicolas Biteau,P. A. Bolle,Monique Bolotin‐Fukuhara,A. J. P. Brown,A. J. P. Brown,Jean‐Marie Buhler,C. Carcano,Giovanna Carignani,Håkan Cederberg,Roland Chanet,Roland Contreras,Marc Crouzet,Bertrand Daignan‐Fornier,E. Defoor,Marco A. Delgado,Jan Demolder,C. Doira,Evelyne Dubois,Bernard Dujon,Andreas Düsterhöft,Dirk Erdmann,M. Esteban,Francis Fabre,Cécile Fairhead,Gérard Faye,Horst Feldmann,Walter Fiers,Marie Claude Francingues-Gaillard,Luís Franco,Laura Frontali,Hiroshi Fukuhara,Linda J. Fuller,Paul Galland,Manda E. Gent,Daniel Gigot,Véronique Gilliquet,Nicolas Glansdorff,André Goffeau,Marcelle Grenson,Paola Grisanti,L.A. Grivell,M. de Haan,M Haasemann,D. Hatat,Janet Hoenicka,Johannes H. Hegemann,Christopher J. Herbert,François Hilger,Susanne Höhmann,C. P. Hollenberg,Kanutte Huse,François Iborra,K. J. Indje,Katsumi Isono,Claude Jacq,Michel Jacquet,C. M. James,J. C. Jauniaux,Yankai Jia,Antonio Moreno Jiménez,Alan J. Kelly,Ulrich Kleinhans,Peter Kreisl,Gerolamo Lanfranchi,Clare M. Lewis,C. G. vanderLinden,Giorgio Lucchini,Katja Lützenkirchen,M.J. Maat,Laurent Mallet,G. Mannhaupet,Enzo Martegani,Aurélie Mathieu,Cornelia Maurer,David J. McConnell,R. K. McKEE,Francine Messenguy,Hans‐Werner Mewes,Francis Molemans,Michelle Montague,Marco Muzi-Falconi,Laura Emilce Navas,Carol S. Newlon,David Noone,C. Pallier,L. Panzeri,Bruce M. Pearson,Javier Perea

出处

期刊：Nature [Springer Nature]
日期：1992-05-01 卷期号：357 (6373): 38-46 被引量：818

链接

nih.govdoi.org

标识

DOI：10.1038/357038a0

摘要

The entire DNA sequence of chromosome III of the yeast Saccharomyces cerevisiae has been determined. This is the first complete sequence analysis of an entire chromosome from any organism. The 315-kilobase sequence reveals 182 open reading frames for proteins longer than 100 amino acids, of which 37 correspond to known genes and 29 more show some similarity to sequences in databases. Of 55 new open reading frames analysed by gene disruption, three are essential genes; of 42 non-essential genes that were tested, 14 show some discernible effect on phenotype and the remaining 28 have no overt function.

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The complete DNA sequence of yeast chromosome III

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