Cadinane sesquiterpenes from Siparuna macrotepala

Abstract Investigation of extracts of leaves and twigs of the Ecuadorian medicinal plant Siparuna macrotepala led characteristically to the isolation of sesquiterpenes of the cadinane group: cadalene, calamenene, 7-hydroxy-calamenene, the dimer of 7-hydroxy-calamenene of S , S -configuration, and two new compounds: 1-hydroxy-calamenene and 1,6-dimethyltetrahydronaphthalenone-4.