Microwave‐enhanced, solvent‐free synthesis of singly and doubly 13C‐labelled trans‐cinnamic acid at the α‐ and β‐carbon positions

Abstract 13 C‐labelled trans ‐cinnamic acid (3‐phenyl‐2‐propenoic acid) has been synthesized in one step using benzaldehyde‐carbonyl‐ 13 C and malonic acid‐2‐ 13 C in the presence of ammonium acetate under microwave irradiation and solvent‐free conditions. Copyright © 2004 John Wiley & Sons, Ltd.