有丝分裂
医学
微管
癌症研究
癌症
细胞生物学
激酶
有丝分裂出口
生物信息学
生物
内科学
细胞周期
后期
标识
DOI:10.1038/nrclinonc.2010.228-c1
摘要
state that many mitotic inhibitors have been unsuccessful in clinical trials in patients with cancer, and conclude that targeting the mitotic process is not useful. While current drugs predominantly target microtubule proteins, targeting other proteins involved in mitosis is in its infancy. Inhibitors of only three (all kinases) of more than 100 mitotic proteins
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