Fast presurgical functional mapping using task-related intracranial high gamma activity

皮质电图 运动皮层 神经科学 大脑定位 医学 功能磁共振成像 辅助电机区 癫痫 初级运动皮层 癫痫外科 功能性电刺激 皮质(解剖学) 物理医学与康复 刺激 心理学
作者
Tianyi Qian,Wenjing Zhou,Zhipei Ling,Shangkai Gao,Hesheng Liu,Bo Hong
出处
期刊:Journal of Neurosurgery [American Association of Neurological Surgeons]
卷期号:119 (1): 26-36 被引量:25
标识
DOI:10.3171/2013.2.jns12843
摘要

Object Electrocorticography (ECoG) is a powerful tool for presurgical functional mapping. Power increase in the high gamma band has been observed from ECoG electrodes on the surface of the sensory motor cortex during the execution of body movements. In this study the authors aim to validate the clinical usage of high gamma activity in presurgical mapping by comparing ECoG mapping with traditional direct electrical cortical stimulation (ECS) and functional MRI (fMRI) mapping. Methods Seventeen patients with epilepsy participated in an ECoG motor mapping experiment. The patients executed a 5-minute hand/tongue movement task while the ECoG signal was recorded. All 17 patients also underwent extraoperative ECS mapping to localize the motor cortex. Eight patients also participated in a presurgical fMRI study. The high gamma activity on ECoG was modeled using the general linear model (GLM), and the regions showing significant gamma power increase during the task condition compared with the rest condition were localized. The maps derived from GLM-based ECoG mapping, ECS, and fMRI were then compared. Results High gamma activity in the motor cortex can be reliably modulated by motor tasks. Localization of the motor regions achieved with GLM-based ECoG mapping was consistent with the localization determined by ECS. The maps also appeared to be highly localized compared with the fMRI activations. Using the ECS findings as the reference, GLM-based ECoG mapping showed a significantly higher sensitivity than fMRI (66.7% for ECoG, 52.6% for fMRI, p < 0.05), while the specificity was high for both techniques (> 97%). If the current-spreading effect in ECS is accounted for, ECoG mapping may produce maps almost identical to those produced by ECS mapping (100% sensitivity and 99.5% specificity). Conclusions General linear model–based ECoG mapping showed a superior performance compared to traditional ECS and fMRI mapping in terms of efficiency and accuracy. Using this method, motor functions can be reliably mapped in less than 5 minutes.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
hailiangzheng完成签到,获得积分10
1秒前
随便取完成签到,获得积分10
1秒前
时尚俊驰发布了新的文献求助10
1秒前
勤奋的如松完成签到,获得积分0
6秒前
粥可温完成签到,获得积分10
8秒前
曾珍发布了新的文献求助10
9秒前
10秒前
hzh完成签到 ,获得积分10
11秒前
gg发布了新的文献求助10
11秒前
勤劳滑板完成签到 ,获得积分10
11秒前
Jerry完成签到,获得积分10
12秒前
MrLiu完成签到,获得积分10
13秒前
冷傲博完成签到,获得积分10
13秒前
jeff完成签到,获得积分10
13秒前
LHZ完成签到,获得积分10
13秒前
所所应助时尚俊驰采纳,获得10
14秒前
影子芳香完成签到 ,获得积分10
15秒前
16秒前
16秒前
不必要再讨论适合与否完成签到,获得积分0
17秒前
无情夏寒完成签到 ,获得积分10
18秒前
慕青应助马士全采纳,获得10
19秒前
xuzj应助科研通管家采纳,获得10
19秒前
Rubby应助科研通管家采纳,获得30
20秒前
SciGPT应助科研通管家采纳,获得10
20秒前
20秒前
20秒前
shiizii应助科研通管家采纳,获得10
20秒前
20秒前
20秒前
20秒前
ludong_0应助科研通管家采纳,获得10
20秒前
YeeYee发布了新的文献求助10
20秒前
冷酷的松思完成签到,获得积分10
20秒前
zgt01发布了新的文献求助10
21秒前
zhang完成签到,获得积分10
21秒前
江中完成签到 ,获得积分10
23秒前
23秒前
阿玖完成签到 ,获得积分10
24秒前
jiaolulu发布了新的文献求助10
26秒前
高分求助中
【提示信息,请勿应助】关于scihub 10000
Les Mantodea de Guyane: Insecta, Polyneoptera [The Mantids of French Guiana] 3000
徐淮辽南地区新元古代叠层石及生物地层 3000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Handbook of Industrial Diamonds.Vol2 1100
Global Eyelash Assessment scale (GEA) 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 550
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4038201
求助须知:如何正确求助?哪些是违规求助? 3575940
关于积分的说明 11373987
捐赠科研通 3305747
什么是DOI,文献DOI怎么找? 1819274
邀请新用户注册赠送积分活动 892662
科研通“疑难数据库(出版商)”最低求助积分说明 815022