多不饱和脂肪酸
六烯酸
水溶液
不饱和度
化学
二十碳五烯酸
花生四烯酸
亚麻酸
亚油酸
脂肪酸
色谱法
有机化学
酶
作者
Kazuo Miyashita,Eiichi Nara,Toru Ota
摘要
The relative oxidative stability of six kinds of typical polyunsaturated fatty acids (PUFAs) was investigated in an aqueous solution (pH=7.4 at 37°C) with Fe2+-ascorbic acid as a catalyst. The highest stability was shown by docosahexaenoic acid (22: 6n-3, DHA), followed by eicosapentaenoic (20: 5n-3), arachidonic (20: 4n-6), α-linolenic (18: 3n-3), γ-linolenic (18: 3n-6), and linoleic (18: 2n-6, LA) acids, indicating that the stability increased with increasing degree of unsaturation. The significant difference found between α-linolenic and γ-linolenic acids also suggests the higher oxidative stability of n-3 PUFAs than of n-6 PUFAs in an aqueous solution. Moreover, when a mixture of DHA and LA was oxidized in an aqueous solution, the stability increased with increasing molar ratio of DHA to LA in the mixture. This characteristic oxidative stability of PUFAs in the aqueous phase is quite different from that in the neat phase, and can be explained by correlating with the conformation of PUFAs in the aqueous medium.
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